Pathology EMQ template.

Name: Benjamin Clarke

Candidate number:

Theme: Chronic myeloid Leukaemia

 

OPTION LIST

 

A

13q deletion

I

Bortezomib

B

Henoch-schonlein purpura

J

Enlarged, rubbery non-tender nodes

C

BRCA1

K

25-45 years

D

Chlorambucil

L

Trisomy 12

E

Rituximab

M

Chloroquine sulphate

F

Splenomegaly

N

13-20 years

G

65-70 years

O

BCR-ABL

H

Hydroxyurea

P

Imatinib

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. Associated with the aetiology of CML

 

 

2. The mainstay agent used to lower the white cell count

 

 

3. An early clinical sign in the majority of patients

 

 

4. A protein kinase inhibitor used in chronic phase CML or newly diagnosed cases where bone marrow transplantation is no considered first line treatment

 

 

5. The peak age of onset of CML

 

 

 

ANSWERS

1. o

2. h

3. f

4. p

5. k